Anticorps Polyclonal de lapin anti-UXT

UXT Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11047-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of HeLa using 11047-1-AP (same clone as 11047-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 11047-1-AP (UXT antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11047-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 11047-1-AP (same clone as 11047-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 11047-1-AP (UXT antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11047-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 11047-1-AP (same clone as 11047-1-PBS)

  IP result of anti-UXT (IP:11047-1-AP, 3ug; Detection:11047-1-AP 1:300) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 11047-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11047-1-PBS cible UXT dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: UXT Protéine recombinante Ag1513
• Nom complet: ubiquitously-expressed transcript
• Masse moléculaire calculée: 20 kDa
• Poids moléculaire observé: 18 kDa, 45 kDa
• Numéro d’acquisition GenBank: BC008890
• Symbole du gène: UXT
• Identification du gène (NCBI): 8409
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ubiquitously expressed transcript (UXT) is a gene transcription regulator. It can regulate androgen receptor(AR) transcription by concerting with the coreperssor UR1. It is proposed a potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling, for UXT increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC. UXT is possible a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function. It can suppresses cell transformation and mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM

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