Anticorps Recombinant de lapin anti-VCAM-1/CD106

VCAM-1/CD106 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251266C11

N° de cat : 86797-1-PBS

Synonymes

CD106, Soluble Vascular Cell Adhesion Molecule-1, Vascular cell adhesion protein 1, V-CAM 1, Vcam1

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Galerie de données de validation

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  WB analysis using 86797-1-RR (same clone as 86797-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86797-1-RR (Vcam1/CD106 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86797-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86797-1-PBS cible VCAM-1/CD106 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: VCAM-1/CD106 Protéine recombinante Eg3821
• Nom complet: vascular cell adhesion molecule 1
• Masse moléculaire calculée: 81 kDa
• Poids moléculaire observé: 100-110 kDa
• Numéro d’acquisition GenBank: NM_012889.1
• Symbole du gène: Vcam1
• Identification du gène (NCBI): 25361
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843).

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