Anticorps Recombinant de lapin anti-VCAM-1/CD106

VCAM-1/CD106 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240597C2

N° de cat : 98059-1-RR

Synonymes

CD106, VCAM-1, Vcam1, Vcam 1, 240597C2

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Galerie de données de validation

• 

  FC experiment of mouse bone marrow cells using 98059-1-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse VCAM-1/CD106 Rabbit Recombinant Antibody (98059-1-RR, Clone:240597C2) or 0.25 ug Isotype Control and PE-conjugated Goat Anti-Rabbit IgG. Cell were then stained with APC Anti-Mouse CD11b. Cells were not fixed.

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  Affinity and Kinetic Characterization of 98059-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98059-1-RR against Mouse VCAM-1/CD106 were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en cytométrie: cellules médullaires de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98059-1-RR cible VCAM-1/CD106 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: vascular cell adhesion molecule 1
• Masse moléculaire calculée: 81 kDa
• Numéro d’acquisition GenBank: CAA47989.1
• Symbole du gène: VCAM-1
• Identification du gène (NCBI): 22329
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843).

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