Anticorps Recombinant de lapin anti-VEGFR2/CD309

VEGFR2/CD309 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240214D7

N° de cat : 83366-1-PBS

Synonymes

VEGFR-2/Kdr, Kdr, 240214D7, CD309, Flk 1

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Galerie de données de validation

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  WB analysis of mouse lung using 83366-1-RR (same clone as 83366-1-PBS)

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 83366-1-RR (VEGFR2/KDR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83366-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP00394-1

  Cytometric bead array standard curve of MP00394-1, MOUSE VEGFR2/KDR Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83366-1-PBS. Detection antibody: 83366-3-PBS. Standard: Eg0703. Range: 0.625-80 ng/mL.

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  Cytometric bead array standard curve of MP00394-3

  Cytometric bead array standard curve of MP00394-3, MOUSE VEGFR2/KDR Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83366-1-PBS. Detection antibody: 83366-2-PBS. Standard: Eg0703. Range: 5-80 ng/mL.

• 

  Affinity and Kinetic Characterization of 83366-1-RR

  Biolayer interferometry (BLl) kinetic assays of 83366-1-RR against Mouse VEGFR2/KDR were performed. The affinity constant is 1.88 nM.

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Informations sur le produit

83366-1-PBS cible VEGFR2/CD309 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: VEGFR2/CD309 Protéine recombinante Eg0703
• Nom complet: kinase insert domain protein receptor
• Masse moléculaire calculée: 150KD
• Poids moléculaire observé: 150-190 kDa
• Numéro d’acquisition GenBank: NM_010612.2
• Symbole du gène: VEGFR-2
• Identification du gène (NCBI): 16542
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

VEGFR2, also named CD309, KDR, and FLK1, is a receptor for VEGF or VEGFC. VEGFR2 which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In the case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGFR2 functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis, and sprouting.

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