Anticorps Recombinant de lapin anti-VEGFR2/CD309

VEGFR2/CD309 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

240214D7

N° de cat : CL647-98027-2

Synonymes

Kdr, Krd 1, Flk1, Flk 1, 6130401C07

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Galerie de données de validation

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  FC experiment of bEnd.3 using CL647-98027-2

  1x10^6 bEnd.3 cells were stained with 0.25 ug CoraLite® Plus 647 Anti-Mouse VEGFR2/CD309 Rabbit Recombinant Antibody (CL647-98027-2, Clone: 240214D7) (red), or Isotype Control (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules bEnd.3,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98027-2 cible VEGFR2/CD309 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: kinase insert domain protein receptor
• Masse moléculaire calculée: 150KD
• Numéro d’acquisition GenBank: NM_010612.2
• Symbole du gène: VEGFR-2
• Identification du gène (NCBI): 16542
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

VEGFR2, also named as CD309, KDR and FLK1, is a receptor for VEGF or VEGFC. VEGFR2 which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGFR2 functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.

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