Anticorps Polyclonal de lapin anti-VNN1

• Phare
• Validé par KD/KO

VNN1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21745-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of BxPC-3 using 21745-1-AP (same clone as 21745-1-PBS)

  BxPC-3 cells were subjected to SDS PAGE followed by western blot with 21745-1-AP (VNN1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21745-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 21745-1-AP (same clone as 21745-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21745-1-AP (VNN1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21745-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse kidney using 21745-1-AP (same clone as 21745-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 21745-1-AP (VNN1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21745-1-PBS in a different storage buffer formulation.

• 

  WB analysis of PC-13 using 21745-1-AP (same clone as 21745-1-PBS)

  PC-13 cells were subjected to SDS PAGE followed by western blot with 21745-1-AP (VNN1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21745-1-PBS in a different storage buffer formulation.

• 

  WB analysis of PC-13 using 21745-1-AP (same clone as 21745-1-PBS)

  PC-13 cells were subjected to SDS PAGE followed by western blot with 21745-1-AP (VNN1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21745-1-PBS in a different storage buffer formulation.

• 

  WB analysis of BxPC-3 using 21745-1-AP (same clone as 21745-1-PBS)

  BxPC-3 cells were subjected to SDS PAGE followed by western blot with 21745-1-AP (VNN1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21745-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21745-1-PBS cible VNN1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: VNN1 Protéine recombinante Ag16501
• Nom complet: vanin 1
• Masse moléculaire calculée: 513 aa, 57 kDa
• Poids moléculaire observé: 55-72 kDa
• Numéro d’acquisition GenBank: BC096268
• Symbole du gène: VNN1
• Identification du gène (NCBI): 8876
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

VNN1(Vascular non-inflammatory molecule 1) is also named as Vanin-1, Pantetheinase, Tiff66. It is a GPI-anchored 70-kDa protein with a high degree of homology with GPI-80 (also known as VNN2), a molecule expressed by human phagocytes and involved in leukocyte adhesion and migration. Vanin-1 is predominantly expressed by resident tissue cells and acts at the level of epithelial cells and surrounding hematopoietic cells by paracrine 2-Mercaptoethylamine release(PMID:17163446). The full length VNN1 has a signal peptide, a propeptide and six glycosylation sites. According to some authors, the variations which varied between 55 and 72kDa may be due to different degrees of glycosylation of the protein and cleavage (JOSE A et al. 2001).

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