Anticorps Polyclonal de lapin anti-VSX1

VSX1 Polyclonal Antibody for WB, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23566-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse eye using 23566-1-AP (same clone as 23566-1-PBS)

  mouse eye tissue were subjected to SDS PAGE followed by western blot with 23566-1-AP (VSX1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23566-1-PBS in a different storage buffer formulation.

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  WB analysis of Raji using 23566-1-AP (same clone as 23566-1-PBS)

  Raji cells were subjected to SDS PAGE followed by western blot with 23566-1-AP (VSX1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23566-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse eye using 23566-1-AP (same clone as 23566-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse eye tissue using 23566-1-AP (VSX1 antibody) at dilution of 1:100 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23566-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23566-1-PBS cible VSX1 dans les applications de WB, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: VSX1 Protéine recombinante Ag19222
• Nom complet: visual system homeobox 1
• Masse moléculaire calculée: 365 aa, 38 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC126228
• Symbole du gène: VSX1
• Identification du gène (NCBI): 30813
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

VSX1(visual system homeobox 1) is a member of the Vsx1 group of vertebrate paired-like homeodomain transcription factors locating to the nucleus. Mutations in the VSX1 gene in keratoconus have been reported in many studies. VSX1 is considered important in ocular development and is particularly involved in the developing cornea (PMID:21139977). And previous studies have identified that Vsx1 participates in regulating retinal progenitor proliferation, differentiation and functional maintenance of bipolar cells (PMID:25150888). It was demonstrated that Vsx1 express in embryonic craniofacial, adult corneal, and adult retinal cDNA libraries.VSX1 mRNA has been found in the outer tier of the inner nuclear layer of the human retina and the cornea (PMID: 21139977).

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