Anticorps Monoclonal anti-WDR1

• Phare
• Validé par KD/KO

WDR1 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2D11E1

N° de cat : 67937-1-PBS

Synonymes

WD repeat containing protein 1, NORI-1, NORI 1, AIP1, Actin-interacting protein 1

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Galerie de données de validation

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  WB analysis using 67937-1-Ig (same clone as 67937-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67937-1-Ig (WDR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67937-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 67937-1-Ig (same clone as 67937-1-PBS)

  WB result of WDR1 antibody (67937-1-Ig; 1:10000; incubated at room temperature for 1.5 hours) with sh-Control and sh-WDR1 transfected HEK-293 cells. This data was developed using the same antibody clone with 67937-1-PBS in a different storage buffer formulation.

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  WB analysis of rat testis using 67937-1-Ig (same clone as 67937-1-PBS)

  rat testis tissue were subjected to SDS PAGE followed by western blot with 67937-1-Ig (WDR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67937-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67937-1-PBS cible WDR1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: WDR1 Protéine recombinante Ag30967
• Nom complet: WD repeat domain 1
• Masse moléculaire calculée: 606 aa, 66 kDa
• Poids moléculaire observé: 65-66 kDa
• Numéro d’acquisition GenBank: BC030541
• Symbole du gène: WDR1
• Identification du gène (NCBI): 9948
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

WDR1, which belongs to the WD repeat AIP1 family, also known as AIP1, is a 606 amino acid protein that localizes to the cytoskeleton. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WDR1 induces the disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PMID:15629458, 27557945, 29751004). WDR1 mutations may impair the ability of WDR1 to regulate cofilin-mediated actin depolymerization, and are associated with periodic fever, immunodeficiency, and thrombocytopenia syndrome (PMID: 27557945,27994071,29751004).

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