Anticorps Polyclonal de lapin anti-WDR62

WDR62 Polyclonal Antibody for IHC, IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23404-1-PBS

Synonymes

C19orf14, WD repeat domain 62, WD repeat-containing protein 62

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Galerie de données de validation

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  IP experiment of HEK-293T using 23404-1-AP (same clone as 23404-1-PBS)

  IP result of anti-WDR62 (IP:23404-1-AP, 4ug; Detection:23404-1-AP 1:500) with HEK-293T cells lysate 1320 ug. This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 23404-1-AP (same clone as 23404-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 23404-1-AP (WDR62 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 23404-1-AP (same clone as 23404-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 23404-1-AP (WDR62 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IF Staining of hTERT-RPE1 using 23404-1-AP (same clone as 23404-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed hTERT-RPE1 cells using WDR62 antibody (23404-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 23404-1-AP (same clone as 23404-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using WDR62 antibody (23404-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23404-1-PBS cible WDR62 dans les applications de IHC, IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: WDR62 Protéine recombinante Ag19865
• Nom complet: WD repeat domain 62
• Masse moléculaire calculée: 1518 aa, 166 kDa
• Poids moléculaire observé: 180 kDa
• Numéro d’acquisition GenBank: BC017261
• Symbole du gène: WDR62
• Identification du gène (NCBI): 284403
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The WD40-repeat protein 62 (WDR62) is a scaffold protein that recruits different components of the JNK signaling pathway to regulate several human diseases including neurological disorders, infertility, and tumorigenesis (PMID: 33937237). Moreover, WDR62 participates in diverse biological processes, especially mitotic spindle organization via regulating centriole biogenesis and the function of centriole-associated protein (PMID: 35093571).

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