Anticorps Polyclonal de lapin anti-WDR77

WDR77 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10115-1-PBS

Synonymes

WDR 77, WD45, WD repeat-containing protein 77, Nbla10071, Methylosome protein WDR77

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Galerie de données de validation

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  WB analysis using 10115-1-AP (same clone as 10115-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10115-1-AP (WDR77 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10115-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach using 10115-1-AP (same clone as 10115-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 10115-1-AP (WDR77 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10115-1-PBS in a different storage buffer formulation.

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Informations sur le produit

10115-1-PBS cible WDR77 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: WDR77 Protéine recombinante Ag0147
• Nom complet: WD repeat domain 77
• Masse moléculaire calculée: 50 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: BC001679
• Symbole du gène: WDR77
• Identification du gène (NCBI): 79084
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

WDR77, other named p44, MEP-50, is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. Normally, WDR77 locates in the nucleus, such as in prostate epithelial cells. However, it localized to the cytoplasm in prostatic intraepithelial neoplasia and prostate cancer cells. Nuclear WDR77 mediates the growth inhibition and differentiation. WDR may involve in the biogenesis of small nuclear ribonucleoprotein particles.

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