Anticorps Polyclonal de lapin anti-WNT4

WNT4 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14371-1-PBS

Synonymes

WNT 4, UNQ426/PRO864, SERKAL, Protein Wnt-4, Protein Wnt 4

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Galerie de données de validation

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  IHC staining of human kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14371-1-AP (WNT4 antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14371-1-AP (WNT4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14371-1-AP (WNT4 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of human hepatocirrhosis using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 14371-1-AP (WNT4 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of human hepatocirrhosis using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 14371-1-AP (WNT4 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14371-1-AP (WNT4 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14371-1-AP (WNT4 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 14371-1-AP (same clone as 14371-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using WNT4 antibody (14371-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002), CL594-Phalloidin (red). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 14371-1-AP (same clone as 14371-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using WNT4 antibody (14371-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14371-1-PBS cible WNT4 dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: WNT4 Protéine recombinante Ag5741
• Nom complet: wingless-type MMTV integration site family, member 4
• Masse moléculaire calculée: 39 kDa
• Poids moléculaire observé: 39-45 kDa
• Numéro d’acquisition GenBank: BC057781
• Symbole du gène: WNT4
• Identification du gène (NCBI): 54361
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

WNT4 belongs to the Wnt family. WNT4 is critical for embryonic organogenesis, but later plays a unique role among Wnt proteins in the development and maintenance of müllerian and reproductive tissues (PMID: 33963381). The mesenchymal stem cells can improve cardiac function after cardiac injury by regulating endothelial cells via the Wnt4/β-catenin signaling pathway (PMID: 20551912). WNT4 may be modified by glycosylation, leading to an increase in molecular weight.

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