Anticorps Polyclonal de lapin anti-WNT6

• Phare
• Validé par KD/KO

WNT6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24201-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of SGC-7901 using 24201-1-AP (same clone as 24201-1-PBS)

  SGC-7901 cells were subjected to SDS PAGE followed by western blot with 24201-1-AP (WNT6 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24201-1-AP (same clone as 24201-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24201-1-AP (WNT6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24201-1-AP (same clone as 24201-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24201-1-AP (WNT6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 24201-1-AP (same clone as 24201-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 24201-1-AP (WNT6 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 24201-1-AP (same clone as 24201-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 24201-1-AP (WNT6 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24201-1-PBS cible WNT6 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: WNT6 Protéine recombinante Ag20889
• Nom complet: wingless-type MMTV integration site family, member 6
• Masse moléculaire calculée: 39 kDa
• Poids moléculaire observé: 42 kDa
• Numéro d’acquisition GenBank: BC004329
• Symbole du gène: WNT6
• Identification du gène (NCBI): 7475
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

WNT6 belongs to the Wnt family. It is ligand for members of the frizzled family of seven transmembrane receptors. WNT6 is likely to signal over only few cell diameters. WNT6 may be together with CAV1 to promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway. And WNT6 is mainly expressed in brain, endometrium epithelium, gastric cancer cell lines and gastric cancer tissues (PMID: 22370641).

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