Anticorps Monoclonal anti-WWOX

WWOX Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, porc, rat, souris

Applications

WB, IHC, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1B8F4

N° de cat : 67725-1-PBS

Synonymes

FRA16D, FOR1, FOR, EC:1.1.1.-, D16S432E

---

Galerie de données de validation

• 

  WB analysis using 67725-1-Ig (same clone as 67725-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67725-1-Ig (WWOX antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67725-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse testis using 67725-1-Ig (same clone as 67725-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 67725-1-Ig (WWOX antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67725-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP51258-1

  Cytometric bead array standard curve of MP51258-1, WWOX Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67725-2-PBS. Detection antibody: 67725-1-PBS. Standard:Ag7969. Range: 0.195-100 ng/mL.

---

Informations sur le produit

67725-1-PBS cible WWOX dans les applications de WB, IHC, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: WWOX Protéine recombinante Ag7969
• Nom complet: WW domain containing oxidoreductase
• Masse moléculaire calculée: 47 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: BC003184
• Symbole du gène: WWOX
• Identification du gène (NCBI): 51741
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

WWOX(WW domain-containing oxidoreductase) is also named as FOR, WOX1 and belongs to the short-chain dehydrogenases/reductases (SDR) family. The gene encodes a 46 kDa protein that contains two WW domains and a short-chain dehydrogenase/reductase domain and the protein is lost or reduced in the majority of many cancer types including breast, prostate, esophageal, lung, stomach, and pancreatic carcinomas and in a large fraction of other cancer types(PMID:17360458). WWOX behaves as a potential tumor-suppressor gene(PMID:15064722). It has 7 isoforms produced by alternative splicing.

{{ptg:RelatedPrimaryAntibodies}}