Anticorps Monoclonal anti-WWP1

• Phare
• Validé par KD/KO

WWP1 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2G8G11

N° de cat : 67804-1-PBS

Synonymes

2G8G11, AIP5, Atrophin-1-interacting protein 5, EC:2.3.2.26, HECT-type E3 ubiquitin transferase WWP1

---

Galerie de données de validation

• 

  WB analysis using 67804-1-Ig (same clone as 67804-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67804-1-Ig (WWP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control. This data was developed using the same antibody clone with 67804-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HaCaT using 67804-1-Ig (same clone as 67804-1-PBS)

  HaCaT cells were subjected to SDS PAGE followed by western blot with 67804-1-Ig (WWP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67804-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

67804-1-PBS cible WWP1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: WWP1 Protéine recombinante Ag30171
• Nom complet: WW domain containing E3 ubiquitin protein ligase 1
• Masse moléculaire calculée: 922 aa, 105 kDa
• Poids moléculaire observé: 95-105 kDa
• Numéro d’acquisition GenBank: BC036065
• Symbole du gène: WWP1
• Identification du gène (NCBI): 11059
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is a multifunction protein containing an N-terminal C2 domain, four tandem WW domains for substrate binding, and a C-terminal catalytic HECT domain for ubiquitin transferring. It is also named as AIP5, Tiul1. WWP1 regulates a variety of cellular biological processes including protein trafficking and degradation, signaling, transcription, and viral budding. WWP1 has been implicated in several diseases, such as cancers, infectious diseases, neurological diseases, and aging(PMID:22051607). It has 6 isoforms produced by alternative splicing.

{{ptg:RelatedPrimaryAntibodies}}