Anticorps Recombinant de lapin anti-XDH

XDH Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242724E3

N° de cat : 85206-3-PBS

Synonymes

XDHA, XD, Xanthine oxidoreductase, Xanthine Oxidase, xanthine dehydrogenase

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Galerie de données de validation

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  WB analysis using 85206-3-RR (same clone as 85206-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85206-3-RR (XDH antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85206-3-PBS in a different storage buffer formulation.

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Informations sur le produit

85206-3-PBS cible XDH dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: xanthine dehydrogenase
• Masse moléculaire calculée: 146 kDa
• Poids moléculaire observé: 147-150 kDa
• Numéro d’acquisition GenBank: NM_000379
• Symbole du gène: XDH
• Identification du gène (NCBI): 7498
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

XDH, also named as XDHA, XO and XD, belongs to the xanthine dehydrogenase family. It catalyzes the last two steps of purine catabolism in man, formation of the end product uric acid from hypoxanthine and xanthine. The mammalian enzyme is synthesized as a dehydrogenase (XDH), which uses NAD as the electron acceptor, but it can be converted into an oxidase (XO) both in vivo and in vitro.This gene encodes a protein of 150 kDa and the 150 kDa polypeptide can be processed into a fragment of 130 kDa and further to 85 kDa by spontaneous proteolytic cleavage(PMID:9989587). In addition, the full length polypeptide can be also partially processed into a 87 kDa and 59 kDa fragments(PMID:21528298). It also can exsit as a homodimer(PMID:9989587).

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