Anticorps Monoclonal anti-YY2

YY2 Monoclonal Antibody for WB, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

1C11A7

N° de cat : 66839-1-PBS

Synonymes

1C11A7, Transcription factor YY2, Yin and yang 2, YY 2, YY-2

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Galerie de données de validation

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  WB analysis of human kidney using 66839-1-Ig (same clone as 66839-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 66839-1-Ig (YY2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66839-1-PBS in a different storage buffer formulation.

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  WB analysis of human placenta using 66839-1-Ig (same clone as 66839-1-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 66839-1-Ig (YY2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66839-1-PBS in a different storage buffer formulation.

• 

  WB analysis of MCF-7 using 66839-1-Ig (same clone as 66839-1-PBS)

  MCF-7 cells were subjected to SDS PAGE followed by western blot with 66839-1-Ig (YY2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66839-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66839-1-PBS cible YY2 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: YY2 Protéine recombinante Ag25373
• Nom complet: YY2 transcription factor
• Masse moléculaire calculée: 372 aa, 46 kDa
• Poids moléculaire observé: 46 kDa
• Numéro d’acquisition GenBank: BC137217
• Symbole du gène: YY2
• Identification du gène (NCBI): 404281
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

YY2 (Yin-Yang 2) encodes a zinc finger transcription factor similarity to the well-characterized YY1 that locating to nucleus. Both proteins recognize an identical DNA-binding motifs with a high homologous Zinc Finger region, and these transcription factors can act as activators or repressors when bound to DNA (PMID:26350623). It is reported that YY2 is placental mammal-specific and is absent in marsupial and non-mammalian vertebrate species (PMID:16377127). YYs are play an important role in multiple developmental processes , such as implantation, cell differentiation, X inactivation, imprinting and organogenesis (PMID:27191592). YY2 is expressed in kindey, liver, spleen and testicle but not in the colon (PMID:15087442). A 41kDa band could be detected.

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