Anticorps Recombinant de lapin anti-ZAK

ZAK Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250559E6

N° de cat : 81161-2-PBS

Synonymes

AZK, EC:2.7.11.25, HCCS 4, HCCS-4, Leucine zipper- and sterile alpha motif-containing kinase

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Galerie de données de validation

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  WB analysis using 81161-2-RR (same clone as 81161-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 81161-2-RR (ZAK antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81161-2-PBS in a different storage buffer formulation.

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  WB analysis using 81161-2-RR (same clone as 81161-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 81161-2-RR (ZAK antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81161-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 81161-2-RR

  Biolayer interferometry (BLl) kinetic assays of 81161-2-RR against Human ZAK were performed. The affinity constant is 0.28 nM.

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Informations sur le produit

81161-2-PBS cible ZAK dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ZAK Protéine recombinante Ag30599
• Nom complet: sterile alpha motif and leucine zipper containing kinase AZK
• Masse moléculaire calculée: 91 kDa
• Poids moléculaire observé: 91kDa, 51 kDa
• Numéro d’acquisition GenBank: BC001401
• Symbole du gène: ZAK
• Identification du gène (NCBI): 51776
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ZAK(sterile-alpha motif and leucine zipper containing kinase AZK) is also named as MLTK, MAPKKK, mlklak, MLK7, AZK, MLT, MRK, HCCS-4, MAP3K20 and belongs to the MAPKKK family. It is a mitogen-activated protein kinase kinase kinase (MAP3K) that activates the stress-activated protein kinase/c-jun N-terminal kinase pathway and activates NF-kappaB. ZAK contributes to regulation of DNA damage checkpoints through a p38 gamma-independent pathway. This protein has 3 isoforms produced by alternative splicing with the MW of 91 kDa (ZAK alpha), 51 kDa (ZAK beta) and 35 kDa.

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