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Anticorps Polyclonal de lapin anti-ZFAND5

ZFAND5 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25048-1-PBS

Synonymes

AN1-type zinc finger protein 5, ZFAND5A, Zinc finger A20 domain-containing protein 2, ZNF216

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using ZFAND5 Polyclonal antibody (25048-1-AP)

    WB analysis using 25048-1-AP (same clone as 25048-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25048-1-AP (ZFAND5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25048-1-PBS in a different storage buffer formulation.

Informations sur le produit

25048-1-PBS cible ZFAND5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène ZFAND5 Protéine recombinante Ag19311
Nom complet zinc finger, AN1-type domain 5
Masse moléculaire calculée 213 aa, 23 kDa
Poids moléculaire observé 23-35 kDa
Numéro d’acquisition GenBankBC027707
Symbole du gène ZFAND5
Identification du gène (NCBI) 7763
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ZFAND5 is Involved in protein degradation via the ubiquitin-proteasome system and may act by anchoring ubiquitinated proteins to the proteasome. It plays a role in ubiquitin-mediated protein degradation during muscle atrophy and in the regulation of NF-kappa-B activation and apoptosis. It can inhibit NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. It also inhibits tumor necrosis factor (TNF), IL-1, and TLR4-induced NF-kappa-B activation in a dose-dependent manner.

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