Anticorps Polyclonal de lapin anti-ZFP42

ZFP42 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 31790-1-AP

Synonymes

hREX-1, Reduced expression protein 1, REX1, REX-1, Zfp-42

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Galerie de données de validation

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  WB analysis using 31790-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31790-1-AP (ZFP42 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HL-60, cellules LNCaP, cellules PC-3, cellules Raji

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

31790-1-AP cible ZFP42 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ZFP42 Protéine recombinante Ag36112
• Nom complet: zinc finger protein 42 homolog (mouse)
• Poids moléculaire observé: 47 kDa
• Numéro d’acquisition GenBank: BC160056
• Symbole du gène: ZFP42
• Identification du gène (NCBI): 132625
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The ZFP42, also known as REX1, is a transcriptional regulator and a member of the zinc finger protein family. It is specifically highly expressed in pluripotent stem cells, such as embryonic stem cells, and is one of the key molecules for maintaining cell pluripotency and self-renewal capacity. Its expression level rapidly declines with cell differentiation, making it widely used as a reliable marker for the pluripotent state. Studies have shown that ZFP42 is involved in inhibiting differentiation programs and maintaining stemness by regulating the transcription of downstream target genes. Additionally, its abnormal expression in various tumors suggests that it may be involved in tumorigenesis and development, making it an important subject in the research of regenerative medicine, developmental biology, and oncology.

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