Anticorps Recombinant de lapin anti-ZMPSTE24

ZMPSTE24 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241288C11

N° de cat : 84547-1-PBS

Synonymes

FACE-1, FACE1, FACE 1, EC:3.4.24.84, CAAX prenyl protease 1 homolog

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Galerie de données de validation

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  WB analysis using 84547-1-RR (same clone as 84547-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84547-1-RR (ZMPSTE24 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84547-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84547-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84547-1-RR against Human ZMPSTE24 were performed. The affinity constant is 1.87 nM.

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Informations sur le produit

84547-1-PBS cible ZMPSTE24 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ZMPSTE24 Protéine recombinante Ag33613
• Nom complet: zinc metallopeptidase (STE24 homolog, S. cerevisiae)
• Masse moléculaire calculée: 475 aa, 55 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC037283
• Symbole du gène: ZMPSTE24
• Identification du gène (NCBI): 10269
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ZMPSTE24(CAAX prenyl protease 1 homolog) gene encodes a zinc metalloproteinase involved in the processing of farnesylated proteins(PubMed: 10373325). The significance of ZMPSTE24 in human disease stems from its role as an enzyme necessary for the correct processing and maturation of lamin A ,an intermediate filament component of the nuclear envelope (PubMed: 16297189).

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