Anticorps Recombinant de lapin anti-ZMYND10

ZMYND10 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251276H4

N° de cat : 86430-1-PBS

Synonymes

BLU, LUCA12.4, Protein BLu, Zinc finger MYND domain-containing protein 10

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Galerie de données de validation

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  WB analysis using 86430-1-RR (same clone as 86430-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86430-1-RR (ZMYND10 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86430-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 86430-1-RR (same clone as 86430-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86430-1-RR (ZMYND10 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86430-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 86430-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86430-1-RR against Human ZMYND10 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

86430-1-PBS cible ZMYND10 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ZMYND10 Protéine recombinante Ag5808
• Nom complet: zinc finger, MYND-type containing 10
• Masse moléculaire calculée: 50 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC033732
• Symbole du gène: ZMYND10
• Identification du gène (NCBI): 51364
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ZMYND10 (Zinc finger MYND domain-containing protein 10), also known as BLU, encodes a 50-kDa protein containing an MYND-type zinc finger DNA-binding domain in the C-terminus that is commonly found in transcription repressors. ZMYND10 is highly enriched in ciliated cells compared with that in nonciliated cells and is expressed in motile ciliated tissues in mice (PMID: 23891471). ZMYND10 is a tumor suppressor that can induce apoptosis, arrest cell cycle, and inhibit proliferation and angiogenesis in different tumors (PMID: 29601588, 31801619).

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