Anticorps Polyclonal de lapin anti-ZNF280B

ZNF280B Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32519-1-PBS

Synonymes

Zinc finger protein 632, Zinc finger protein 280B, Zinc finger protein 279, Suppressor of hairy wing homolog 2, SUHW2

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Galerie de données de validation

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  WB analysis using 32519-1-AP (same clone as 32519-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32519-1-AP (ZNF280B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32519-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32519-1-PBS cible ZNF280B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ZNF280B Protéine recombinante Ag38544
• Nom complet: zinc finger protein 280B
• Masse moléculaire calculée: 62kDa，543aa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: NM_080764.3
• Symbole du gène: ZNF280B
• Identification du gène (NCBI): 140883
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ZNF280B belongs to the family of zinc finger proteins, a transcription factor that is mainly involved in the regulation of gene expression. In prostate cancer cells, ZNF280B induces p53 nuclear export, leading to subsequent proteasomal degradation. Therefore, ZNF280B has pro-growth and pro-survival functions in prostate cancer cells. In addition to this, ZNF280B has a promotional role in gastric and lung cancer development, and its potential as a tumor therapeutic target can be explored in the future.

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