Anticorps Polyclonal de lapin anti-ZNF410

• Phare
• Validé par KD/KO

ZNF410 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14529-1-PBS

Synonymes

Zinc finger protein APA 1, Zinc finger protein 410, APA1, APA 1, Another partner for ARF 1

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Galerie de données de validation

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  WB analysis using 14529-1-AP (same clone as 14529-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14529-1-AP (ZNF410 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14529-1-PBS in a different storage buffer formulation.

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  WB analysis using 14529-1-AP (same clone as 14529-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14529-1-AP (ZNF410 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14529-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14529-1-PBS cible ZNF410 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ZNF410 Protéine recombinante Ag6028
• Nom complet: zinc finger protein 410
• Masse moléculaire calculée: 52 kDa
• Poids moléculaire observé: 52-67 kDa
• Numéro d’acquisition GenBank: BC050683
• Symbole du gène: ZNF410
• Identification du gène (NCBI): 57862
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ZNF410 (Zinc Finger Protein 410) is a transcription factor involved in the regulation of gene expression, particularly in the context of fetal hemoglobin (HbF) repression and chromatin remodeling. This protein is highly conserved among mammals and plays a crucial role in erythroid cells. The study found that ZNF410 uniquely silences HbF by activating its sole target gene, CHD4, a known HbF repressor in erythroid cells. (PMID: 40158221)

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