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Anticorps Polyclonal de lapin anti-ZNF768

ZNF768 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 33035-1-PBS

Synonymes

Zinc finger protein 768

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using ZNF768 Polyclonal antibody (33035-1-AP)

    WB analysis using 33035-1-AP (same clone as 33035-1-PBS)

    HeLa cells lysate was subjected to SDS PAGE followed by western blot with 33035-1-AP (ZNF768 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33035-1-PBS in a different storage buffer formulation.

Informations sur le produit

33035-1-PBS cible ZNF768 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène ZNF768 Protéine recombinante Ag37794
Nom complet zinc finger protein 768
Masse moléculaire calculée60 kDa
Poids moléculaire observé70 kDa
Numéro d’acquisition GenBankBC013760
Symbole du gène ZNF768
Identification du gène (NCBI) 79724
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Zinc finger protein 768 (ZNF768) is a zinc finger protein that is crucial in linking oncogenic RAS signaling to cellular senescence and proliferation control. It is a transcription factor that associates with euchromatin and promoter regions of many genes in a cell type-specific manner. ZNF768 is required for cell growth and survival, and its depletion induces a strong proliferative and pro-apoptotic response in several cell lines in vitro. ZNF768 is also involved in regulating cell cycle effectors and p53 targets, with its overexpression sufficient to bypass RAS-induced senescence in a p53-dependent manner (PMID: 34404770; 35419475).

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