Anticorps Polyclonal de lapin anti-ZYG11A

ZYG11A Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30597-1-PBS

Synonymes

Protein zyg 11 homolog A, ZYG11

---

Galerie de données de validation

• 

  WB analysis using 30597-1-AP (same clone as 30597-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30597-1-AP (ZYG11A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30597-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 30597-1-AP (same clone as 30597-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30597-1-AP (ZYG11A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30597-1-PBS in a different storage buffer formulation.

• 

  IF Staining of K-562 using 30597-1-AP (same clone as 30597-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed K-562 cells using ZYG11A antibody (30597-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 30597-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

30597-1-PBS cible ZYG11A dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ZYG11A Protéine recombinante Ag30166
• Nom complet: zyg-11 homolog A (C. elegans)
• Masse moléculaire calculée: 86 kDa
• Poids moléculaire observé: 48 kDa
• Numéro d’acquisition GenBank: NM_001004339
• Symbole du gène: ZYG11A
• Identification du gène (NCBI): 440590
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ZYG11A is a member of the Zyg11 protein family that functions as a target recruitment subunit of an E3 ubiquitin ligase complex playing a central role in the degradation of a regulatory protein involved in cell cycle regulation. ZYG11A is over-expressed in NSCLC tumor tissues and correlates with more aggressive clinical characteristics. Also ZYG11A gene constitutes a novel target for IGF1 action in endometrial cancer cells (PMID: 26771237, 31320996). This antibody is specific to isoform 2 of ZYG11A with a predicted molecular mass of 48 kDa.

{{ptg:RelatedPrimaryAntibodies}}