Anticorps Polyclonal de lapin anti-ZnT3

ZnT3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17363-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 17363-1-AP (same clone as 17363-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17363-1-AP (ZnT3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17363-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 17363-1-AP (same clone as 17363-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain using 17363-1-AP (ZnT3 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17363-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 17363-1-AP (same clone as 17363-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain using 17363-1-AP (ZnT3 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17363-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17363-1-PBS cible ZnT3 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ZnT3 Protéine recombinante Ag10735
• Nom complet: solute carrier family 30 (zinc transporter), member 3
• Masse moléculaire calculée: 388 aa, 42 kDa
• Poids moléculaire observé: 42 kDa, 48 kDa
• Numéro d’acquisition GenBank: BC028358
• Symbole du gène: ZnT3
• Identification du gène (NCBI): 7781
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ZnT3, encoded by SLC30A3, is a member of SLC30A family which is zinc transporter sequestrating cytosolic zinc into intracellular compartments or effluxing zinc to the extracellular space. Excessive zinc level can cause neuron apoptosis and lead to cognitive impairments. Znt3 facilitates the transport and storage of zinc in synaptic vesicles. Abnormal ZnT3 expression has been linked to some neurodegenerative disorders.

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