Anticorps Polyclonal de lapin anti-fibrosin

fibrosin Polyclonal Antibody for Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11356-1-PBS

Synonymes

FBRS, Probable fibrosin-1, FBSH, FBS1, FBS

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Galerie de données de validation

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  WB analysis of mouse kidney using 11356-1-AP (same clone as 11356-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 11356-1-AP (fibrosin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11356-1-PBS in a different storage buffer formulation.

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  WB analysis of MCF-7 using 11356-1-AP (same clone as 11356-1-PBS)

  MCF7 cells were subjected to SDS PAGE followed by western blot with 11356-1-AP (fibrosin antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11356-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11356-1-PBS cible fibrosin dans les applications de Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: fibrosin Protéine recombinante Ag1870
• Nom complet: fibrosin
• Masse moléculaire calculée: 52 kDa
• Poids moléculaire observé: 48-52 kDa
• Numéro d’acquisition GenBank: BC014212
• Symbole du gène: fibrosin
• Identification du gène (NCBI): 64319
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Fibrosin is a lymphokine secreted by activated lymphocytes that induces fibroblast proliferation FBRS (or FBS1) gene, encoding fibrosin (or fibrosin-1), was first cloned by Prakash et al. and was found to be able to stimulate several biological activities related to scarring as a fibrogenic lymphokine. Fibrosin is secreted by activated lymphocytes that induce fibroblast proliferation. In vitro application of fibrosin stimulates expression of alpha smooth muscle actin fibers and plays an important role in up regulating the appearance of myofibroblasts during wound healing and possibly in fibrotic diseases. Fibrosin is also implicated in alcohol-induced hepatic fibrosis in vivo.

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