Anticorps Monoclonal anti-5-methylcytosine

5-methylcytosine Monoclonal Antibody for IHC, Dot Blot, ELISA, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

m5C

Applications

IHC, Dot Blot, ELISA, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2C9G9

N° de cat : 68301-1-PBS

Synonymes

m5C, RNA methylation, 5mC



Informations sur le produit

68301-1-PBS cible 5-methylcytosine dans les applications de IHC, Dot Blot, ELISA, Indirect ELISA et montre une réactivité avec des échantillons m5C

Réactivité m5C
Hôte / Isotype Mouse / IgG2b
Clonalité Monoclonal
Type Anticorps
Immunogène Composé
Nom complet 5-methylcytosine
Symbole du gène
Identification du gène (NCBI)
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

In eukaryotes, 5-methylcytosine in DNA (5mC) and its oxidized derivatives (5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC)) are the most prominent modifications and have been suggested to contribute to epigenetic gene regulation through a variety of different mechanisms. m5C has also been found in mRNA, rRNA and tRNA of representative organisms from all kinds of species. As reversible epigenetic modifications, m5C modifications of RNA affect the fate of the modified RNA molecules and play important roles in various biological processes including RNA stability control, protein synthesis, and transcriptional regulation (PMID: 35365216). This antibody can recognize both 5mC in DNA and m5C in RNA.

Protocol for Dot Blot:
https://www.ptglab.com/protocol/68301-1-IgDotBlot.pdf

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