Anticorps Monoclonal anti-p57Kip2

p57Kip2 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1A12H3

N° de cat : 66794-1-PBS

Synonymes

CDKN1C, KIP2, p57, Cyclin-dependent kinase inhibitor p57, Cyclin-dependent kinase inhibitor 1C

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Galerie de données de validation

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  WB analysis using 66794-1-Ig (same clone as 66794-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66794-1-Ig (CDKN1C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66794-1-PBS in a different storage buffer formulation.

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  WB analysis using 66794-1-Ig (same clone as 66794-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66794-1-Ig (p57Kip2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66794-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 66794-1-Ig (same clone as 66794-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 66794-1-Ig (CDKN1C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66794-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 66794-1-Ig (same clone as 66794-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 66794-1-Ig (p57Kip2 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66794-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 66794-1-Ig (same clone as 66794-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 66794-1-Ig (p57Kip2 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66794-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66794-1-PBS cible p57Kip2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: p57Kip2 Protéine recombinante Ag19927
• Nom complet: cyclin-dependent kinase inhibitor 1C (p57, Kip2)
• Masse moléculaire calculée: 316 aa, 32 kDa
• Poids moléculaire observé: 57 kDa
• Numéro d’acquisition GenBank: BC067842
• Symbole du gène: p57 Kip2/CDKN1C
• Identification du gène (NCBI): 1028
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CDKN1C, also named as p57KIP2 and KIP2, belongs to the CDI family. CDKN1C is a potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. It is a negative regulator of cell proliferation. CDKN1C may play a role in maintenance of the non-proliferative state throughout life.

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