Anticorps Recombinant de lapin anti-NGFR/TNFRSF16

NGFR/TNFRSF16 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242465H4

N° de cat : 85192-1-PBS

Synonymes

Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor, Low affinity neurotrophin receptor p75NTR, Gp80-LNGFR, CD271

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Galerie de données de validation

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  WB analysis using 85192-1-RR (same clone as 85192-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85192-1-RR (p75NTR antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85192-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85192-1-RR

  Biolayer interferometry (BLl) kinetic assays of 85192-1-RR against Rat NGFR/TNFRSF16 were performed. The affinity constant is 0.148 nM.

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Informations sur le produit

85192-1-PBS cible NGFR/TNFRSF16 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: nerve growth factor receptor (TNFR superfamily, member 16)
• Masse moléculaire calculée: 45 kDa
• Poids moléculaire observé: 70-75 kDa
• Symbole du gène: Ngfr
• Identification du gène (NCBI): 24596
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

p75NTR, also named TNFRSF16, Gp80-LNGFR, p75 ICD, and CD271, is a low-affinity receptor that can bind to NGF, BDNF, NT-3, and NT-4. It mediates cell survival as well as cell death of neural cells. The antibody is specific to NGFR.

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