Anticorps Recombinant de lapin anti-Phospho-RCC1 (Ser11)

Phospho-RCC1 (Ser11) Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

230056B10

N° de cat : 83630-1-PBS

Synonymes

phospho-RCC1(Ser11), RCC1, RCC1 I, CHC1, 230056B10

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Galerie de données de validation

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  WB analysis using 83630-1-RR (same clone as 83630-1-PBS)

  Non-treated and nocodazole treated HeLa cells were subjected to SDS PAGE followed by western blot with 83630-1-RR (phospho-RCC1(Ser11) antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours. The membrane was stripped and re-blotted with GAPDH (60004-1-Ig) subsequently. This data was developed using the same antibody clone with 83630-1-PBS in a different storage buffer formulation.

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Informations sur le produit

83630-1-PBS cible Phospho-RCC1 (Ser11) dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: regulator of chromosome condensation 1
• Masse moléculaire calculée: 48 kDa
• Poids moléculaire observé: 45-50 kDa
• Numéro d’acquisition GenBank: NM_001048194
• Symbole du gène: RCC1
• Identification du gène (NCBI): 1104
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against human phospho-CHC1(Ser11) antigen.

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