Custom Antibody Services

Leveraging over two decades of experience in antibody development, Proteintech scientists can fulfill all your custom antibody needs starting from antigen design and synthesis to large-scale production, characterization and conjugation of your antibody. Moreover, our Antigen-Specific B-Cell Cloning & Engineering (ABCE™) platform enables multi-species recombinant antibody discovery of desired targets with a rapid turnaround.

+ Years

Antibody Development Experience

K+

In-house Manufactured Antibodies

K

Targets Covered

K+

Product Citations

20+ Years

Antibody Development Experience

15K+

In-house Manufactured Antibodies

13K

Targets Covered

200K+

Product Citations

Our Services

Recombinant antibody development & engineering

Develop highly specific recombinant monoclonal antibodies, utilizing the Proteintech single B cell-based ABCE™ platform:

  • Fab, F(ab’) fragments and scFv, scFv-Fc, VHH-Fc
  • Chimeric and Bi-specific antibodies
  • Custom VHH/Nanobody service
  • Choose from a wide variety of host species
  • Antibody characterization is available for customized clones

Custom conjugation and formulation

Proteintech has the flexibility to deliver several custom conjugation and formulation options to fulfil your individual project requirements:

  • Conjugation of various fluorescent dyes, enzymes, peptides and oligonucleotides
  • Site-specific and stoichiometric conjugation ​ ​
  • Carrier-free, ultra low endotoxin and other formulations available on request.

GMP-grade manufacturing

Proteintech supports your regulatory needs in the diagnostics, drug discovery and cell & gene therapy industry with production of antibodies in compliance with ISO 13485:2016. Learn more.

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Our Recombinant Platform

Proteintech’s custom antibody service utilizes its proprietary ABCE™ (Antigen-Specific B-Cell Cloning & Engineering) platform, which provides the following advantages:​

  • High-yield expression: Enables stable and efficient production of recombinant monoclonal antibodies.
  • Preserves native VH-VL pairings: Maintains natural antibody specificity and functionality, unlike phage display
  • Efficient and fast: Produces more positive clones from fewer cells in less time compared to traditional hybridoma methods.
  • High-throughput capability: Supports rapid development of Uni-rAb™ off-the-shelf antibodies.
  • Precise Antigen Design: Our scientists bring decades of experience in generating antigens tailored to your specific needs, including challenging targets and post-translational modifications.
Projected timeline for custom antibody development on the ABCE platform workflow graphic ​

Projected timeline for custom recombinant antibody development on the ABCE™ platform.