AATF Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 10282-1-AP

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Freight/Packing

Con: 58 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:500-1:1000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
apoptosis antagonizing transcription factor

Calculated molecular weight:
63 kDa

Observed molecular weight:
63kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AATF

Synonyms
AATF, CHE 1, CHE1, DED, Protein AATF, Rb binding protein Che 1, Traube
Background

Apoptosis antagonizing transcription factor (AATF) is a nuclear phosphoprotein of 523 amino acids and contains an extremely acidic domain and a putative leucine zipper characteristic of transcription factors. AATF was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. Overexpression of this gene interfered with MAP3K12 induced apoptosis. AATF also binds Rb and the core of pol II, and may be part of transcription regulatory complex.


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