ADAM2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13952-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse testis tissue, human testis tissue, mouse testis tissue

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ADAM metallopeptidase domain 2

Calculated molecular weight:
82 kDa

Observed molecular weight:
50-55 kDa, 65-75 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADAM2

Synonyms
ADAM 2, ADAM metallopeptidase domain 2, ADAM2, Cancer/testis antigen 15, CRYN1, CRYN2, CT15, Fertilin subunit beta, FTNB, PH 30, PH 30b, PH30, PH30 beta
Background

Members of the ADAM (a disintegrin and metalloprotease) family are multifunctional, transmembranous proteins consisting of pro-, metalloprotease, disintegrin, cysteine-rich, epidermal growth factor-like, transmembrane, and cytoplasmic tail domains. Fertilin, a heterodimeric protein complex composed of a(ADAM1) and b(ADAM2) subunits present on the sperm surface, has been believed to mediate adhesion and fusion between the sperm and egg plasma membranes. ADAM2-deficient mouse sperm is also defective in adhesion to and fusion with the egg membrane (PMID:16407235). It has 2 isoforms produced by alternative splicing and 5 glycosylation sites.


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