ARL8B Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 13049-1-AP

Featured Product KD/KO validated

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Con: 30 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
fetal human brain tissue, human brain tissue, mouse brain tissue, NIH/3T3 cells

Positive IHC detected in:
human stomach tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ADP-ribosylation factor-like 8B

Calculated molecular weight:
186aa,22 kDa

Observed molecular weight:
22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARL8B

Synonyms
ARL10C, ARL8B, FLJ10702, Gie1
Background

ARL8B ( ADP-ribosylation factor-like 8B) , also known as ARL10C or GIE1, is a small GTPase of the Arl-family, that is associated with the lysosome. ARL8A interacts with Tubulin, and plays a role in lysosome motility, as well as in chromosomal segregation. ARL8B plays a role in the spatial distribution and positioning of lysosomes. Arl8b is regarded as a regulator of endosome to lysosome trafficking pathways of special significance for host defense.


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