ASAH1 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 11274-1-AP

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Con: 22 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
rat lung tissue, human lung tissue, mouse brain tissue, mouse heart tissue, SH-SY5Y cells

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human breast cancer tissue

Positive IF detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Purification method:
Antigen affinity purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
N-acylsphingosine amidohydrolase (acid ceramidase) 1

Calculated molecular weight:
44 kDa

Observed molecular weight:
60-65 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

AC, Acid ceramidase, Acylsphingosine deacylase, ASAH, ASAH1, HSD 33, PHP, PHP32, Putative 32 kDa heart protein

ASAH1, also named as AC, ACDase, Acid CDase, PHP32 and ASAH, belongs to the acid ceramidase family. It is a 32 kDa heart protein. ASAH1 is a lipid hydrolase that catalyzes the conversion of ceramide (cer) into sphingosine (SPH) and a free fatty acid. Mutation of ASAH1 will cause the Farber lipogranulomatosis (FL) which also known as Farber disease (FD). ASAH1 is highly expressed in Heart. And it is first synthesized as an 55-60 kDa precursor and subsequently processed to the mature, heterodimeric enzyme (40 + 13 kDa) in the endosomes/lysosomes.

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