ATG4B Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 15131-1-AP

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Freight/Packing

Con: 81 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, fetal

Positive IP detected in:
mouse skeletal muscle tissue

Positive IHC detected in:
human pancreas cancer tissue, mouse heart tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ATG4 autophagy related 4 homolog B (S. cerevisiae)

Calculated molecular weight:
44 kDa

Observed molecular weight:
44 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ATG4B

Synonyms
APG4B, ATG4B, AUTL1, Autophagin 1, Cysteine protease ATG4B, hAPG4B, KIAA0943
Background

ATG4B(autophagy 4) is also named as APG4B, AUTL1, KIAA0943 and belongs to the peptidase C54 family. It is a homolog of yeast Apg4, a cysteine protease involved in autophagy and is a cytoplasmic enzyme. This protein is highly expressed in skeletal muscle, with lower expression in heart, liver, and pancreas and no expression is detected in fetal tissues by the northern blot. ATG4B is widely expressed in tumor cell lines(PMID:12446702). It has 5 isoforms produced by alternative splicing.


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