Aurora B Antibody 1 Publications

Mouse Monoclonal| Catalog number: 60098-1-Ig |CloneNo.: 3H1

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Con: 120 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HeLa cells, mouse thymus tissue

Positive IHC detected in:
human lymphoma tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
aurora kinase B

Calculated molecular weight:
39.2 kDa

Observed molecular weight:
39-45 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AURKB

Synonyms
AIK2, AIM 1, AIM1, ARK 2, ARK2, AurB, AURKB, Aurora B, aurora kinase B, Aurora related kinase 2, Aurora/IPL1 related kinase 2, IPL1, STK 1, STK12, STK5
Background

Aurora B(AURKB) is also named as aurora kinase B, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5 and belongs to the Aurora subfamily. Aurora kinase B is a chromosomal passenger serine/threonine protein kinase that regulates accurate chromosomal segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachments, and regulation of the mitotic checkpoint(PMID:18311747). Expression levels of AURKB are increased in the anaplastic thyroid carcinoma cell lines ARO, Cal 62, and KAT-4(PMID:15562011).


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