AXIN2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 20540-1-AP

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Con: 70 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells, BxPC-3 cells, MDA-MB-453s cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
axin 2

Calculated molecular weight:
843aa,94 kDa

Observed molecular weight:
93-100 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

AXIL, axin 2, Axin like protein, AXIN2, Axis inhibition protein 2, Conductin

Axis inhibition protein2 (AXIN2), also known as Coductin or Axil, is a multidoman scaffold protein that negatively regulate Wnt signaling. AXIN2 can directly interact with beta-catenin and GSK3B. AXIN2 has a number of phosphorylation sites, and also can undergo poly(ADP-ribosy)lation by tankyrase TNKS and TNKS2. Poly(ADP-ribosy)lated AXIN2 then get unbiquitinated by RNF146 and leads to its degradation and subsequent activation of Wnt signaling. AXIN2 is localized in the cytoplasm and its mutaion is involved in colorectal cancer. Catalgo#20540-1-AP is a rabbit polyclonal antibdy raised against a 34 amino acid N-terminal of human AXIN2.

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