BAK Antibody 25 Publications

Rabbit Polyclonal| Catalog number: 14673-1-AP

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Freight/Packing

Con: 45 μg/150 μl

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Species specificity:
human, mouse, rat, sheep

Positive WB detected in:
Jurkat cells, rat skeletal muscle tissue, A431 cells, RAW 264.7 cells, mouse heart tissue

Positive IHC detected in:
human tonsillitis tissue, human lymphoma tissue, human tonsillitis tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:6000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
BCL2-antagonist/killer 1

Calculated molecular weight:
23 kDa

Observed molecular weight:
28 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BAK1

Synonyms
Apoptosis regulator BAK, BAK, BAK LIKE, BAK1, CDN1
Background

BAK1, also named as BAK, BCL2L7 and CDN1, belongs to the Bcl-2 family. In the presence of an appropriate stimulus, BAK1 accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. (PMID:17157251) BAK1 gene product primarily enhances apoptotic cell death following an appropriate stimulus. It can inhibit cell death in an Epstein-Barr virus-transformed cell line.


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