BMP5 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66370-1-Ig |CloneNo.: 1G6C10

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Con: 150 μg/150 μl

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Species specificity:
human, pig

Positive WB detected in:
pig lung tissue, pig liver tissue

Recommended dilution:
WB : 1:1000-1:4000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
bone morphogenetic protein 5

Calculated molecular weight:
454aa,52 kDa

Observed molecular weight:
52 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BMP5

Synonyms
BMP 5, BMP5, bone morphogenetic protein 5
Background

Bone morphogenetic protein-5 (BMP5), is a member of the transforming growth factor-beta (TGF-beta) superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. BMP5 may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. BMP5 is differentially regulated in multiple human cancers.


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