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BTG2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 22339-1-AP

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Con: 39 μg/150 μl

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Tested Applications

Applications:
IHC, ELISA
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BTG2 Antibody IHC human small intestine tissue 22339-1-AP

Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 22339-1-AP( BTG2 Antibody) at dilution of 1:200 (under 10x lens).

BTG2 Antibody IHC human small intestine tissue 22339-1-AP

Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 22339-1-AP( BTG2 Antibody) at dilution of 1:200 (under 40x lens).

Species specificity:
human
Positive IHC detected in:
human small intestine tissue, human kidney tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
IHC : 1:50-1:500
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
BTG2 fusion protein Ag17819
Full name:
BTG family, member 2
Calculated molecular weight:
158aa,17 kDa
Observed molecular weight:
GenBank accession number:
BC105949
Gene ID (NCBI):
7832
Gene symbol
BTG2
Synonyms
BTG family member 2, BTG family, member 2, BTG2, PC3, Protein BTG2, TIS21

Background

Protein BTG2, the anti-proliferative human homolog of murine Pc3/Tis21, belongs to the BTG/Tob family. This family has structurally related proteins that appear to have anti-proliferative properties. It has been demonstrated that BTG2 is p53-inducible and is involved in cell cycle control and cellular response to DNA damage (PMID: 8944033). As a transcriptional co-regulator, BTG2 has been shown to interact with CAF1 and POP2, and works as a co-activator of ERa-mediated transcription via a CCR4-like complex (PMID: 18974182).


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