CA12 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 15180-1-AP

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Freight/Packing

Con: 64 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
BxPC-3 cells, BxPC-3 cells, C6 cells, HEK-293 cells, PC-3 cells

Positive IHC detected in:
human kidney tissue

Positive FC detected in:
HEK-293 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
carbonic anhydrase XII

Calculated molecular weight:
39 kDa

Observed molecular weight:
44kd,75-80kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CA12

Synonyms
CA XII, CA12, Carbonate dehydratase XII, Carbonic anhydrase 12, carbonic anhydrase XII, CAXII, FLJ20151, HsT18816, Tumor antigen HOM RCC 3.1.3
Background

CA12 belongs to the alpha-carbonic anhydrase family. It reversible hydration of carbon dioxide. Overexpression of the zinc enzyme CA12 is observed in certain human cancers. The structure reveals a prototypical CA fold; however, two CA12domains associate to form an isologous dimer, an observation that is confirmed by studies of the enzyme in solution.


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