CD11B/Integrin alpha M Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 20991-1-AP

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Con: 81 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HL-60 cells, Jurkat cells

Positive IHC detected in:
human spleen tissue, human liver tissue, human spleen tissue, human tonsillitis tissue

Positive FC detected in:
HL-60 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
integrin, alpha M (complement component 3 receptor 3 subunit)

Calculated molecular weight:
93 kDa

Observed molecular weight:
110-170 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ITGAM

Synonyms
CD11B, CR 3 alpha chain, CR3A, Integrin alpha M, ITGAM, MAC 1, MAC1A, MO1A, Neutrophil adherence receptor, SLEB6
Background

ITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. ITGAM is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. ITGAM is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The antibody is specific to ITGAM.


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