Validation Data Gallery
|Sample-dependent, check data in validation data gallery|
20991-1-AP targets CD11B/Integrin Alpha M in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
|Host / Isotype||Rabbit / IgG|
|Full Name||integrin, alpha M (complement component 3 receptor 3 subunit)|
|Calculated molecular weight||93 kDa|
|Observed molecular weight||110-170 kDa|
|GenBank accession number||NM_000632|
|Gene ID (NCBI)||3684|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
ITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. ITGAM is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. ITGAM is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The antibody is specific to ITGAM.
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