CDC34 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10964-2-AP

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Freight/Packing

Con: 36 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human pancreas tissue, human brain tissue

Positive IP detected in:
mouse testis tissue, HEK-293 cells

Positive IHC detected in:
human prostate cancer tissue

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cell division cycle 34 homolog (S. cerevisiae)

Calculated molecular weight:
34 kDa

Observed molecular weight:
34 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CDC34

Synonyms
CDC34, E2 CDC34, UBC3, UBCH3, UBE2R1, Ubiquitin protein ligase R1
Background

CDC34 is also named as UBCH3, UBE2R1(Ubiquitin-conjugating enzyme E2 R1) and belongs to the ubiquitin-conjugating enzyme family. Cdc34 enzyme is itself a substrate for the type of polyubiquitin modification that is known to cause targeting of proteins for degradation. It is phosphorylated in vivo, providing yet another potential means for control of its activity. And the predominantly nuclear localization of this enzyme suggests that substrate molecules relevant to its cell cycle function are similarly located within the nucleus(PMID:8164658). Human CDC34 could substitute efficiently for yeast CDC34(PMID:8248134). It can form a homodimer(PMID:8383676).


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