CPEB1 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 13274-1-AP

Featured Product KD/KO validated

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Con: 35 μg/150 μl

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Species specificity:
human, mouse, rat, Asteroidea

Positive WB detected in:
A375 cells, A375 cells, human heart tissue

Positive IHC detected in:
human liver cancer tissue, human breast cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cytoplasmic polyadenylation element binding protein 1

Calculated molecular weight:
486aa,54 kDa

Observed molecular weight:
54 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CPEB1

Synonyms
CEBP, CPE binding protein 1, CPE BP1, CPEB, CPEB1, FLJ13203, h CEBP, hCPEB 1
Background

CPEB1, also named as CEBP, CPEB and CPE-BP1, contains two RRM (RNA recognition motif) domains and belongs to the RRM CPEB family. It is a sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. CPEB1 regulated translation is a key process involved in insulin signaling. This is a rabbit polyclonal antibody raised against residues near the C terminus of human CPEB1. This antibody may recognize several bands, but only ~56kDa band is the right one, other(40~50kDa) is un-specific bands.


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