CPLX2 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 18149-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

Be the first to review this product



Con: 50 μg/150 μl

Choose size:

Please visit your regions distributor:

Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, human brain tissue, mouse brain tissue

Positive IP detected in:
SH-SY5Y cells

Positive IHC detected in:
human brain tissue

Positive IF detected in:
A549 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
complexin 2

Calculated molecular weight:
134aa,15 kDa

Observed molecular weight:
18-20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

921 L, complexin 2, Complexin II, CPLX2, CPX 2, CPX II, CPX2, Hfb1, Synaphin 1

Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Neuronal specific complexin 1 (CPLX1) has inhibitory and stimulatory effects on exocytosis by clamping trans-SNARE complexes in a prefusion state and promoting conformational changes to facilitate membrane fusion following cell stimulation. Complexin2 (CPLX2) is a pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals, it is downregulated in schizophrenic patients suffering from depression, animal models of depression and neurological disorders such as Huntington's disease in which depression is a major symptom.

to top