CPOX Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 12211-1-AP

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human liver tissue, HepG2 cells, human liver tissue, Jurkat cells, K-562 cells

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human medulloblastoma tissue, human liver tissue

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
coproporphyrinogen oxidase

Calculated molecular weight:
454aa,50 kDa

Observed molecular weight:
36 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CPOX

Synonyms
Coprogen oxidase, Coproporphyrinogen oxidase, Coproporphyrinogenase, COX, CPO, CPOX, CPX, HCP
Background

CPOX(Coproporphyrinogen-III oxidase, mitochondrial) is also named as CPO and CPX. Human CPO is a 76 kDa protein that is active as a homodimer in the mitochondrial intermembrane pace(PMID:16159891).Mutations in human CPO gene predict the clinical outcome of the disease, with either hepatic hereditary coproporphyria or hematological manifestations of erythropoietic harderoporphyria.CPOX has a transit peptide of 110 aa and the chain contains 344 aa.


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