CX3CL1 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 10108-2-AP

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Freight/Packing

Con: 22 μg/150 μl

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Species specificity:
human

Positive WB detected in:
PC-3 cells, human brain tissue, PC-3 cells

Positive IHC detected in:
human small intestine tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chemokine (C-X3-C motif) ligand 1

Calculated molecular weight:
42 kDa

Observed molecular weight:
90-100 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CX3CL1

Synonyms
ABCD 3, C X3 C motif chemokine 1, C3Xkine, CX3CL1, CXC3, CXC3C, FKN, fractalkine, neurotactin, NTN, NTT, SCYD1, Small inducible cytokine D1
Background

Chemokines direct the trafficking of white blood cells in immune surveillance, playing a key role in inflammatory and infectious diseases such as AIDS. The human CX3C chemokine carries the chemokine domain on top of an extended mucin-like stalk. CX3CL1 is synthesized as a 50-75kDa precursor and undergoes glycosylation to yield two mature forms: a 100kDa cell membrane bound form and an 85kDa soluble form which is released from the cell surface.The soluble CX3C chemokine has potent chemoattractant activity for T cells and monocytes, and the cell-surface-bound protein, which is induced by primary proinflammatory signals in activated primary endothelial cells, promotes strong adhesion of those leukocytes.


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