CXCR4 Antibody 5 Publications

Mouse Monoclonal| Catalog number: 60042-1-Ig |CloneNo.: 4B5E4

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Freight/Packing

Con: 150 μg/150 μl

Choose size:

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Species specificity:
human, mouse

Positive WB detected in:
K-562 cells, Jurkat cells, U-937 cells

Positive FC detected in:
Jurkat cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Mouse

Purification method:
Caprylic Acid/Ammonium Sulfate Precipitation

Isotype:
IgM

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chemokine (C-X-C motif) receptor 4

Calculated molecular weight:
352aa,40 kDa

Observed molecular weight:
60~70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CXCR4

Synonyms
CD184, CXC R4, CXCR 4, CXCR4, CXCR4B, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, LESTR, SDF 1 receptor, WHIM
Background

The chemokine receptor CXCR4, a 7-transmembrane protein on cell surface, acts with the CD4 protein to support HIV entry into cells. CXCR4 is highly expressed in brain and heart, white blood cells, vascular endothelial cells, and umbilical cord endothelial cells. Several CXCR4 isoforms have been identified with molecular weights of 47, 50, 62 and 98kDa. The 62-64kDa CXCR4 is predominantly ubiquitinated and is preferentially associated with CD4. This antibody recognizes the 62kd CXCR4.


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